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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
27.88
Human Site:
Y1341
Identified Species:
47.18
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
Y1341
V
M
R
L
D
D
T
Y
S
F
Q
V
I
N
K
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
Y1341
V
M
R
L
D
D
T
Y
S
F
Q
V
I
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
Y1341
V
M
R
L
D
D
T
Y
S
F
Q
V
I
N
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
Y1341
V
M
R
L
D
D
A
Y
S
F
Q
V
I
S
K
Rat
Rattus norvegicus
NP_001101888
2143
241191
Y1341
V
M
R
L
D
D
A
Y
S
F
Q
V
I
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
Y1352
V
L
R
L
D
D
T
Y
T
F
Q
V
I
N
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
Y1336
I
M
R
L
D
D
T
Y
S
F
Q
V
I
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
F1301
V
A
R
H
D
D
A
F
S
L
H
I
I
H
N
Honey Bee
Apis mellifera
XP_393800
2028
231830
A1242
K
V
V
D
V
R
C
A
L
Y
T
I
M
P
I
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
T917
D
T
M
I
F
D
R
T
A
Q
T
L
P
R
I
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
P902
G
W
I
G
H
V
T
P
S
Q
P
M
G
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
Q1244
S
I
E
E
T
S
L
Q
P
P
Q
D
V
R
E
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
L1036
F
S
T
L
I
K
T
L
D
P
V
K
A
L
G
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
I1055
N
Q
T
V
K
E
V
I
P
P
L
I
E
T
F
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
93.3
N.A.
40
0
6.6
20
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
100
N.A.
60
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
22
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
58
65
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
0
8
8
0
8
0
0
0
0
0
0
8
0
8
% E
% Phe:
8
0
0
0
8
0
0
8
0
50
0
0
0
8
8
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
8
8
8
8
8
0
0
8
0
0
0
22
58
0
15
% I
% Lys:
8
0
0
0
8
8
0
0
0
0
0
8
0
0
58
% K
% Leu:
0
8
0
58
0
0
8
8
8
8
8
8
0
8
0
% L
% Met:
0
43
8
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
36
8
% N
% Pro:
0
0
0
0
0
0
0
8
15
22
8
0
8
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
15
58
0
0
0
0
% Q
% Arg:
0
0
58
0
0
8
8
0
0
0
0
0
0
15
0
% R
% Ser:
8
8
0
0
0
8
0
0
58
0
0
0
0
15
0
% S
% Thr:
0
8
15
0
8
0
50
8
8
0
15
0
0
8
0
% T
% Val:
50
8
8
8
8
8
8
0
0
0
8
50
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _